ea0092ps3-30-08 | Thyroid Physiology in Periphery & Development Basic | ETA2023
Pires Carolina
, Saramago Ana
, M. Moura Margarida
, Li Jing
, Marques Ines
, Cabrera Rafael
, Machado Ana
, Grunewald Thomas
, Leite Valeriano
, Cavaco Branca
Introduction: Forkhead box E1 (FOXE1) gene encodes a transcription factor crucial for thyroid morphogenesis, differentiation, and function. We previously found evidence of the involvement of a rare germline FOXE1 variant in familial non-medullary thyroid carcinoma (FNMTC) etiology. FNMTC most common subtype is papillary thyroid carcinoma (PTC), and family members frequently present thyroid follicular nodular disease (FND). Germline FOXE1 mu...